Figure S4.
Panel A shows data from Visit 1, while Panel B shows data from a follow-up visit. Each scatter plot compares individuals who returned to health (RTH) and those who remained symptomatic (Symptoms). The x-axes of all scatter plots are labeled RTH and Symptoms. The y-axes are labeled with different biomarkers: Endotoxin (endotoxin units per milliliter), LBP (micrograms per milliliter), sCD14 (micrograms per milliliter), and IFABP (picograms per milliliter). Each symbol represents results from a single participant, and bars indicate the mean with standard error of the mean (SEM). The Mann-Whitney U test was used for statistical analysis, and ns indicates not significant (p greater than 0.05). In Panel A, the scatter plots show the distribution of Endotoxin, LBP, sCD14, and IFABP levels at Visit 1. In Panel B, the scatter plots show the distribution of the same biomarkers at the follow-up visit. The data points are scattered around the mean values, with no significant differences observed between the RTH and Symptoms groups for any of the biomarkers at either visit.
Serum biomarkers in Lyme disease patients returning to health versus those with long-term symptoms. (A and B) Comparison of the indicated serum markers at visit 1 (A) and follow-up visit (B), between individuals who returned to health (RTH) and those who remained symptomatic (symptoms). Bars indicate the mean ± SEM; each symbol represents results from single participant. Statistical analyses were conducted using the Mann–Whitney U test; ns, not significant (P > 0.05).