Panel A shows a heat map reporting Cohen's d values for CD36 colocalization with caveolin-1 in the whole cell, center, and periphery regions for CD36WT and CD36G12V. Panel B shows a heat map reporting Cohen's d values for CD36 and Fyn colocalization with and without TSP-1 in the whole cell, center, and periphery regions for CD36WT and CD36G12V. Panel C shows a heat map comparing CD36 and pSFK colocalization with and without TSP-1 in the whole cell, center, and periphery regions for CD36WT and CD36G12V.
Effect sizes (Cohen’s d) complementing the statistical testing P values of the colocalization experiments presented in Fig. 5. (A–C) Cohen’s d comparing pairwise colocalization measures derived from experimental samples to their coincidental values (nullTR) for CD36-Cav-1 colocalization (A), CD36-Fyn colocalization (B), and CD36-pSFK colocalization (C). Blue color intensity of each table entry reflects the level of significance (P value) as described in Fig. 5. Cohen’s d is reported for only those cases where the colocalization is deemed significant via statistical testing (P value ≤ 0.05; as shown in Fig. 5), visually captured by darker shading. Empty entries thus belong to cases without significant colocalization, visually captured by light shading. Cohen’s d and statistical significance (-log10(P value)) overall correlate well with each other. Cav-1, caveolin-1.