Figure 1.
Panel A: A violin plot comparing current age among alive patients by CVID type. The horizontal axis represents CVID type with two categories: No known genetic defect and Monogenic CVID. The vertical axis represents current age in years, ranging from 0 to 90. The plot shows the kernel density distribution of age. Embedded boxplots display the median, interquartile range (IQR; 25th to 75th percentiles), and whiskers extending to 1.5 times the IQR. Black dots indicate the mean. Patients with monogenic CVID tend to be younger compared to those with no known genetic defect. Panel B: A violin plot comparing age at disease onset by CVID type. The horizontal axis represents CVID type with two categories: No known genetic defect and Monogenic CVID. The vertical axis represents age at disease onset in years, ranging from 0 to 100. The plot shows the kernel density distribution of age at disease onset. Embedded boxplots display the median, interquartile range (IQR; 25th to 75th percentiles), and whiskers extending to 1.5 times the IQR. Black dots indicate the mean. Patients with monogenic CVID exhibit earlier disease onset compared to those with no known genetic defect.
Violin plots comparing age distributions between patients with monogenic CVID and patients with no known genetic defect. (A) Current age among alive patients, stratified by CVID type. (B) Age at disease onset, stratified by CVID type. Violin plots depict the kernel density distribution of age. Embedded boxplots show the median (line) and IQR (25th–75th percentiles), with whiskers extending to 1.5 × IQR. Black dots indicate the mean. Between-group comparisons were performed using the Wilcoxon rank-sum test. IQR, interquartile range.