The diagram is divided into two sections: Wild-type SorLA and SorLA deletion. In the Wild-type SorLA section, SorLA interacts with the B cell receptor (BCR) and localizes to endolysosomal compartments. Antigens are shown binding to BCRs, which are then internalized and processed. In the SorLA deletion section, there is an increase in surface BCR, decreased BCR endocytosis, reduced antigen trafficking, diminished peptide presentation, and a weakened humoral response. The diagram includes labels for SorLA, BCR, antigen, peptide, MHC II, plasma cell, and antibody, showing their interactions and flow within the B cell.