Figure AC5.
Panel A shows a model with states O1, O2, C, and I, where O1 transitions to O2, C, and I through various rate constants. Panel B depicts a model with states C, O1, O2, and I, illustrating transitions between these states through different rate constants. Panel C presents a generic four-state diagram with states O1, O2, C, and I, showing all possible unidirectional transitions between these states.
Models with substates. Channels V activate by voltage; otherwise, V and C have the same properties. (A and B) Similar to models in Figs. AC2 and AC3, with a sub-conductance open state substituted for . (C) A generic four-state diagram to illustrate its 12 potential unidirectional transitions.