Figure AC4.
Panel A shows a line graph with the x-axis labeled time, milliseconds ranging from 0 to 200 and the y-axis labeled occupancy of Open (O) state ranging from 0 to 0.7. The graph includes a state diagram with transitions labeled with rate constants. The line graph shows a peak around 100 milliseconds. Panel B shows a similar line graph with the same axes and labels. The graph also includes a state diagram with transitions labeled with rate constants. The line graph shows a peak around 100 milliseconds.
Deterministic solutions comparable with the average flux in examples AC2 and AC3. (A) The transients in A correspond to the model as represented in the state diagram in the same panel; they are solutions of the system of equations in Box AC1. (B) The transients in panel B are the corresponding solutions of the system of equations that describe the modified state model represented in the same panel. The simplified energy pulse pattern is represented at top. 7.6 is the electrical energy required for half activation of the transition (kT = 1 in Eq. 13).