Figure AC2.
Panel A shows a line graph with the y-axis labeled flux, open channel units and the x-axis labeled time, milliseconds. The graph includes multiple lines representing different energy levels, ranging from 0 to 14 kT. The lines show the flux elicited by paired pulses, with variable conditioning on a large test. Panel B presents a scatter plot with trend line with the y-axis labeled suppression and the x-axis labeled decay. The plot includes black and red symbols representing model data and experimental observations, respectively. The black symbols align closely with the line, indicating a strong correlation between decay and suppression. The red symbols show a broader distribution, suggesting variability in experimental observations.
Properties of a couplon with equal C and V open channel currents. Both classes of channels follow the state diagram at top, identical to that of C channels of the preferred model in the main article. Parameters are those listed in Table 1, except rec1_ht, increased to 100 ms (a change needed to achieve flux with a large inactivating component). (A) Simulations of flux. elicited by paired pulses (conditioning and test), implementing variable conditioning on a large test, as in Figs. 6 and 17 of the main article. (B) Decay and suppression measured on the simulations in A. The red symbols represent experimental observations.