Figure 11.
The horizontal axis represents time in milliseconds, ranging from 0 to 120 milliseconds. The vertical axis represents flux in channel units, ranging from 0 to 150. The graph includes multiple lines, each representing a different energy level in kT units. The energy levels range from 3 to 14 kT, with each line color-coded accordingly. The lines show an initial peak in flux, followed by a rapid decline and stabilization at lower flux levels. The top diagram indicates a constant energy pulse of negative 14 kT.
Ca 2+ release flux elicited by constant energy pulses, color-coded in the top diagram. This is the model output to be compared with experimental records of depletion-corrected flux (as in Figs. 4 B, 6 B, or 8 C). Each record is an average of 800 Markov chain realizations. The voltage changes corresponding to each pulse energy are specified in the text. The model parameters used for calculating these and all other averages are always the same, listed in Table 1. Flux, derived from the numbers of V and C channels open via Eq. 7, is given in units of the flux through an open V channel.