Figure 2.
Panel A shows a molecule or chemical reaction diagram with labeled atoms and a pink dotted line indicating a potential clash. The labels include E 455, N 454, A 456, T 457, and L 458. Panel B shows a similar molecule or chemical reaction diagram with the leucine replaced by methionine, indicated by the label M 458 (L 458 M). Green dotted lines indicate potential hydrogen bonds.
Detail of NEATL in DIS6. (A) Detail of NEATL sequence in DIS6. Pink dotted line, potential clash. (B) Same, with highly conserved leucine replaced by methionine, as it is in this isoform in bats and in Nav1.1 and 1.2 in bats and other species of placental mammalian hibernators (Table 2). Green dotted lines, potential hydrogen bonds.