Panel A shows histograms for STAT2 and STAT1 expression in lymphocytes from P3 and two healthy controls (HC1 and HC2). The x-axis represents fluorescence intensity on a logarithmic scale, and the y-axis represents the percentage of cells. Different lines represent untreated samples (US), and samples treated with IFN alpha and IFN gamma. Panel B shows histograms for phosphorylated STAT2 (pSTAT2) expression in P3, HC1, and HC2. The x-axis represents fluorescence intensity on a logarithmic scale, and the y-axis represents the percentage of cells. Different lines represent untreated samples (US), and samples treated with IFN alpha and IFN gamma. Panel C shows histograms for phosphorylated STAT1 (pSTAT1) expression in P3, HC1, and HC2. The x-axis represents fluorescence intensity on a logarithmic scale, and the y-axis represents the percentage of cells. Different lines represent untreated samples (US), and samples treated with IFN alpha and IFN gamma.
Expression of phosphorylated STAT2 (pSTAT2), STAT2, pSTAT1, and STAT1 in lymphocytes derived from P3 and two healthy controls (HC). (A–C) (A) STAT2 and STAT1, (B) pSTAT2 and (C) pSTAT1 expression in lymphocytes after treatment with 10.000 IU/mL IFNγ and 10.000 IU/ml IFNα for 25 min.
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