Figure S1.
P1 shows a timeline for Patient 1, starting with various infections and antibiotic treatments in the first year, followed by MMR-related complications, and later chronic conditions like asthma and Crohn's disease. Treatments include antibiotics, Cotrimoxazole, and Itraconazole. P2 depicts Patient 2's timeline, highlighting infections, MMR complications, and leg cellulitis treated with antibiotics and surgery. P3 illustrates Patient 3's timeline, marked by MMR complications, high-dose IVIG, and treatments with Ruxolitinib and IVIG.
Clinical presentation of the patients. CNS, central nervous system; CS, cortico-steroids; HLH, hemophagocytic lymphohistiocytosis; HSM, hepatosplenomegaly; IVIG, intravenous immunoglobulins; MMR, measles-mumps-rubella vaccine.