Figure S4.
Panel A shows four bar graphs. The x-axis represents different groups: HC, Mother, Baseline, and Post abatacept. The y-axis represents the percentage of each T-cell subset. Panel B shows one bar graph depicting the proportion of CD31-positive CD45RA-positive naïve CD4-positive T cells. The x-axis represents different groups: HC, Mother, Baseline, and Post abatacept. The y-axis represents the percentage of CD31-positive CD45RA-positive naïve CD4-positive T cells. The graphs show changes in T-cell populations before and after abatacept treatment.
Changes in T cell population with abatacept treatment. (A) Frequencies of Treg subsets, including naïve (CD4+FOXP3+CD45RA+CCR7+), central memory (CD4+FOXP3+CD45RA−CCR7+), effector memory (CD4+FOXP3+CD45RA−CCR7−), and effector memory RA (CD4+FOXP3+CD45RA+CCR7−) populations, are shown for HC, mother, and the patient before and after treatment. (B) Proportion of CD8+CD45RA+CD31+ T cells in HC, mother, and the patient before and after treatment. HC, healthy control.