Figure S2.
A heatmap has a grid layout with rows representing mouse tumors and columns representing human tumors. The color scale ranges from light to dark, indicating the level of conservation, with darker colors representing higher conservation values. The top three bars show patient variables, including the assessment of neuroendocrine features and NEPC score. The left side vertical bars show GEMM variables, including phenotype and genotype. Yellow bars at the top of the heatmap indicate the number of GEMMs that match each patient, while the yellow bars on the right side show the number of patients that match each GEMM. Notable regions include clusters of higher conservation values and gaps where conservation is lower.
Additional OncoMatch analyses (related to Fig. 4). OncoMatch heatmap representing conservation of MRs between individual SB tumors (rows, n = 32) and patient tumors (columns, n = 266) from the SU2C cohort. Patient variables (i.e., assessment of neuroendocrine features and NEPC score) are shown on the right three bars, while GEMM variables (i.e., phenotype and genotype) are shown on the top vertical bars. Yellow bars at the right of the heatmaps show the number of GEMMs that match each patient, while the yellow bars on the bottom side show the number of patients that match each GEMM.