Figure 6.
Panel A: A scatter plot showing the correlation between age at implant in years and CD3 T cell counts in cells per cubic millimeter. The plot includes dozens of data points, a regression line, and shows a negative correlation with a Pearson correlation coefficient of minus 0.34 and a p-value of 0.0093. Panel B: A scatter plot showing the correlation between age at implant in years and CD4 T cell counts in cells per cubic millimeter. The plot includes dozens of data points, a regression line, and shows a negative correlation with a Pearson correlation coefficient of minus 0.37 and a p-value of 0.0041. Panel C: A scatter plot showing the correlation between age at implant in years and naïve CD4 T cell counts in cells per cubic millimeter. The plot includes dozens of data points, a regression line, and shows a negative correlation with a Pearson correlation coefficient of minus 0.37 and a p-value of 0.0091. Panel D: A scatter plot showing the correlation between age at implant in years and CD8 T cell counts in cells per cubic millimeter. The plot includes dozens of data points, a regression line, and shows a weak negative correlation with a Pearson correlation coefficient of minus 0.19 and a p-value of 0.17.
Correlation between median T cell subset counts at 12 mo after CTTI and participant age (years) at the time of thymus implantation. Pearson correlation between age (years) and median CD3, CD4, naive CD4, and CD8 T cell counts. Lymphocyte enumeration results for the participant who received alemtuzumab at 3 mo after CTTI are excluded. (A) Median (Q1; Q3) CD4 T cell count (cells/mm3) is 465 (313; 710). (B) Median (Q1; Q3) naive CD4 T cell count (cells/mm3) is 192 (52; 371). (C) Median (Q1; Q3) CD3 T cell count (cells/mm3) is 703 (397; 945). (D) Median (Q1; Q3) CD8 T cell count (cells/mm3) is 104 (55; 240).