An illustration showing an organelle interacting with effector proteins. Excessive calcium ions are depicted affecting dynein/dynactin and kinesin motor proteins. The effector proteins are shown interacting with the motor proteins. The motor proteins are depicted attached to the organelle.
Schematic of rapamycin-inducible motor recruitment. FRB-tagged organelles were directly coupled to FKBP-fused motor domains (kinesin-1 or dynein/dynactin) via rapamycin-induced dimerization, bypassing endogenous effector pathways.