Ruxolitinib reverses premature ovarian failure in patient 2. Data points in black represent time points before ruxolitinib initiation, while those in green and blue represent time points while receiving ruxolitinib at the indicated dose. Serum AMH (A), FSH (B), and LH (C) levels over time relative to ruxolitinib initiation. The dashed lines represent the lower (A) or upper (B and C) limits of normal for these assays.