Figure 1.
Ruxolitinib reverses early hypoparathyroidism in patient 1. Data points in black represent time points before ruxolitinib initiation, while those in green and blue represent time points while receiving ruxolitinib at the indicated dose. A) Serum iPTH over time relative to ruxolitinib initiation. The dashed horizontal line represents the lower limit of normal for this assay. B) Total calcium levels over time relative to ruxolitinib initiation. C) Serum CXCL9 levels over time relative to ruxolitinib initiation. The dashed horizontal line marks the upper limit of normal for this assay.