Clinical validation of DGS clusters using laboratory studies. Examples of laboratory studies with highly significant differences between DGS patients clustered separately. Distributions for lifetime laboratory data were evaluated for DGS patients across laboratory studies used in clustering algorithms and additional serum studies. Kolmogorov-Smirnov pairwise analyses based on Bonferroni adjustment. *p < 1e-5, **p < 1e-10, and ***p < 1e-15.