Figure S4.
Panel A: A line graph with the x-axis represents days post prime, and the y-axis represents anti-RBD total Ig (B T 50). Red dashed lines indicate immunizations, and black triangles indicate serum transfer. Thin lines indicate individual mice, and bold lines indicate group mean. Three groups are shown: mM-only, mM-only with WT serum, and WT. Panel B: A scatter plot showing the number of GC B cells in dLN. The x-axis represents different groups (WT, mM-only, mM-only plus Ig), and the y-axis represents the number of GC B cells in dLN (times 10 to the power of 4). Each dot represents a single mouse, and bars indicate mean plus or minus standard deviation. Panel C: A scatter plot showing the number of RBD-specific GC B cells in dLN. The x-axis represents different groups (WT, mM-only, mM-only plus Ig), and the y-axis represents the number of RBD-specific GC B cells in dLN (times 10 to the power of 4). Each dot represents a single mouse, and bars indicate mean plus or minus standard deviation.
Analysis of serum transfer experiment. Related to Fig. 5. (A) ELISA quantification of anti-RBD total Ig antibodies in the serum measured weekly from day 0 to day 55. Red dashed lines indicate immunizations; black triangles indicate serum transfer. Thin lines indicate individual mice; bold lines indicate the group mean. (B) Number of GC B cells in the dLN. (C) Number of RBD-specific GC B cells in the dLN. Each dot represents a single mouse; bars indicate the mean ± SD. dLN, draining LN.