Figure S5.
The horizontal axis lists five diseases: S H 2 D 1 A, M A G T 1, R U N X 1, G A T A 2, and C E B P A. The vertical axis represents frequency in percent, ranging from zero to one hundred percent. Each bar is divided into segments representing different age groups: less than or equal to ten years, eleven to twenty years, twenty-one to thirty years, thirty-one to forty years, forty-one to fifty years, fifty-one to sixty years, and sixty-one years or older. S H 2 D 1 A shows a high frequency of tumor onset in the less than or equal to ten years age group. M A G T 1 displays a more distributed frequency across various age groups. R U N X 1, G A T A 2, and C E B P A show a broader distribution with notable frequencies in older age groups. The color scheme uses different colors to represent each age group, with a legend on the right indicating the corresponding age ranges.
A comparison of tumor onset age across different monogenic diseases. Patients with SH2D1A variants are from six cases included in this study. Patients with MAGT1 variants are from (30), and those with RUNX1, GATA2, and CEBPA variants are from (31).