Figure 4.
Heatmap with two panels showing Z scores for gene expression. The left panel lists I G H (immunoglobulin heavy chain) genes, and the right panel lists T C R (T-cell receptor) genes. Each cell’s color intensity represents the Z score, ranging approximately from minus 1 to 5. The top annotation bar indicates sample categories: S A P-L P D in red, D E-D L B C L in blue, and non D E-D L B C L in green. The left panel shows differential expression of I G H genes, with relatively higher expression in D L B C L samples. The right panel depicts T C R gene expression, with higher expression in S A P-L P D compared to D L B C L samples. The heat map reveals distinct clustering patterns, indicating differential immune receptor gene expression profiles between S A P-L P D and D L B C L groups.
IgH and TCR genes included in the DEGs. Genes exhibiting significant differences among the DEGs were listed and heat-mapped using Z-scores. The left panel shows IgH genes, and the right panel shows TCR genes. DEGs, differentially expressed genes.