α-Syn and tau pathology are rarely localized in the same neuron. (A–D) Immunofluorescence staining showing rare colocalization of p-α-syn (red) and p-tau (green) in the hippocampus (A and B) and entorhinal cortex (C and D). (E–L) Representative images of select magnified areas from the hippocampus (E–H) and entorhinal cortex (I–L) showing α-syn and tau localization in different compartments of the same cell (see boxed portions of the images) and enlargements ofthese boxed images along the righthand margin of the main figures. Scale bar, 100 µm. All experimental data were verified in at least two independent experiments.