Figure S5.
Ablation of BNST neurons does not alter baseline heart rate in free-moving mice. 24-h heart rate recording of heart rate in freely moving mice. (A) dtA-mediated ablation of IL-1β–responsive BNST neurons in TRAP2 mice (dtA[−], n = 4 mice; dtA[+], n = 4 mice) had no effect on circadian heart rate, dark cycle (active phase) highlighted in gray. This experiment was completed once. (B) dtA-mediated ablation of CRH+ BNST neurons in crh-cre mice (dtA[−], n = 6 mice; dtA[+], n = 4 mice) had no impact on baseline heart rate. PBS-treated mice were used as controls. This experiment was completed once.