RMSD and RMSF plots of TLR7 and UNC93B1 within the complex. (A) The RMSD plot of the protein backbone reflects structural stability over the course of the simulation. The lower RMSD observed for the mutant TLR7 indicates that its structural fold is more stable compared to the wild type. (B) RMSF plots show the residue-level flexibility of TLR7 and UNC93B1, with both proteins exhibiting similar fluctuation profiles across their respective residues.