Patients with overt lymphoid neoplasm (lymphoma). The innermost ring categorizes patients based on the IUIS classification of IEI. The second inner ring details specific IEI diagnoses. The third inner ring shows the identification number of each patient, reporting in parentheses the age at last follow-up; double-underlined patients are those experiencing EBV chronic replication with a viremia >1,000 copies/ml during follow-up, while red bold patients are those who succumbed to lymphoma. The outermost ring specifies the type of lymphoma, reporting in parentheses the age at overt lymphoid neoplasm (lymphoma) diagnosis. EBER-negative lymphomas are displayed in a lighter shade, distinguishing them from EBER-positive lymphomas, which retain the same color shade as their corresponding internal classification rings.