Structural stability of the equilibrated CLDN15 reduced model. (A) Average backbone RMSD from the last 14 ns of the CLDN15 reduced model 105-ns equilibration, colored by each of 24 monomers. (B) Average backbone RMSF from the last 14 ns of the CLDN15 reduced model 105-ns equilibration, for each of 24 monomers.