Figure 3.
Comparison of lipid-binding sites in different detergent-solubilized and liposome-based stabilized pore structures. (A) Comparison of pore structure in the presence of RBCs (cyan) with pore in the presence of MPD (yellow). The zoomed view shows the location of the lipid head group and MPD density. (B) Comparison of pore structure solved in the presence of RBCs (cyan) with pore structure solved in the presence of 10:0 PC liposomes (orange). The zoomed view shows the location of the lipid head group and 10:0 PC density. (C) Comparison of pore structure solved in the presence of RBCs (cyan) with pore structure solved in the presence of C14 PC (green).