Figure 4. UMAP of scRNA-seq data. (A)... | Rockefeller University Press

Figure 4.

$UMAP of scRNA-seq data. (A) UMAPs of gene expression profiles mapped on primary cell data based on 141,646 resting ex vivo cells from Weymar et al. (2022) and 96,547 in vitro cells (45,297 resting and 51,250 activated) from this study. Cells with similar transcriptional profile were divided into 15 different clusters. The locations of cells from the HIV-1+ clone of interest are presented as red dot. (B) Bar graph representing the fraction of HIV-1+ cells that share gene expression profile with each of the 15 clusters from the UMAP. Ex vivo resting cells are presented in gray, in vitro resting cells in blue and in vitro activated cells in red. Refer to the image caption for details.$

UMAP of scRNA-seq data. (A) UMAPs of gene expression profiles mapped on primary cell data based on 141,646 resting ex vivo cells from Weymar et al. (2022) and 96,547 in vitro cells (45,297 resting and 51,250 activated) from this study. Cells with similar transcriptional profile were divided into 15 different clusters. The locations of cells from the HIV-1⁺ clone of interest are presented as red dot. (B) Bar graph representing the fraction of HIV-1⁺ cells that share gene expression profile with each of the 15 clusters from the UMAP. Ex vivo resting cells are presented in gray, in vitro resting cells in blue and in vitro activated cells in red.