Figure 6.
Integration of all proteomic changes gives a “thumbprint” of cellular stress responses. Representative schemes integrating all proteomic changes per each stress (a, starvation; b, H2O2; c, DTT) demonstrate the unique thumbprint of cell remodeling in each of the responses. The entire proteome is divided into organelles represented as colored segments on the circumference. The black bar plot above each organelle gives each protein’s abundance under SD and is sorted in each organelle. Blue (down-regulation) and red (up-regulation) bars demonstrate protein abundance changes. Lines between organelles demonstrate localization changes and are colored according to the destination organelle.