Figure 3.

KLP3A localization and Aurora B localization and activity are not compromised in NOD-expressing cells. (A, C, and E) Representative maximum projections of tubulin, DAPI (blue), KLP3A (red; A), phospho–histone H3–serine 10 (red; C) or phospho–Aurora B (red; E), and NOD (green) for high and low/no NOD-expressing cells. (B, D, and F) Quantification of KLP3A (n = 102 cells; B), phospho–histone H3 (Serine 10; n = 31 cells; D), or phospho–Aurora B (n = 73 cells; F) signals relative to DAPI intensities for high and low/no NOD-expressing cells. There was not a statistically significant difference in levels of KLP3A, phospho–Aurora B, or phospho-H3 (Ser10) between high and no/low NOD-expressing cells. Two-tailed p-values are shown. Error bars represent the SEM. Bars, 10 µm.

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