Subdendritic translocation of αCaMKII correlates with spine remodeling. (A and B) Dendrite coexpressing mGFP-αCaMKII and mCherry stimulated with 0Mg²⁺/Gly for 5 min. Arrows point to spines (red), spine morphological change (pink), new protrusion (yellow), and spine elongation (green). White brackets indicate regions of dendritic CaMKII hot spot (D+). (C) Cumulative distribution and associated histogram of the fold increase in the number of spines on 15-µm dendritic sections, associated with regions revealing dendritic CaMKII accumulation (D+) or not (D−). (D) Histogram of the mean ± SEM increase in spine number classified by spine morphology and associated with regions revealing dendritic CaMKII accumulation (D+) or not (D−). (n = 19 neurons, 154 dendritic sections). *, P < 0.05 two-sided rank sum test. Bars: (A) 2 µm; (B) 5 µm. See also Video 7.