Figure 2.

Dynein arrangement within the 96-nm unit in the distal region. (A) Comparison of the MTD2-8+ structures in wild type (WT) and ida10 (which has significantly reduced amounts of dyneins b, c, d, and e). In wild-type MTD2-8+, a dynein density labeled with two names (such as a/d) is the one whose identity has been previously unsettled between the two species. The black arrows in ida10 MTD2-8+ indicate the missing densities that were determined to be those of dyneins b and d in this study. Bar, 16 nm. (B) Model of the common IDA architecture in the 96-nm unit showing the complete assignment of all major dynein isoforms. The coloring scheme is as follows: red, IDA; light blue, ODA; turquoise, RS; green, DRC; yellow, dynein f IC/LC. The same coloring scheme is used throughout all figures and supplemental figures unless mentioned otherwise. Surface renderings are always positioned with the proximal part on the left and the distal part on the right unless mentioned otherwise.

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