Figure 5.

Recruitment of LGG-1 and RAB-7 on Q cell corpse and proposed model. (A) Still images show the sequence of BFP::RAB-7 and LGG-1::GFP recruitment onto the Q cell corpse (red). Bar, 5 µm. (B) Proposed model of the function of autophagy genes in Q cell corpse degradation. EPG-5 was recruited onto the phagosome during engulfment. ATG-18 was corecruited with RAB-5, and ATG-18 recruitment requires its association with PI(3)P on apoptotic corpses. EPG-5 and ATG-18 are required for RAB-5 recruitment. LGG-1 recruitment occurs at the phagolysosome stage.

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