CK1-γ/Gish regulates PCP-directed morphogenetic processes. (A–C) Wild-type and gish LOF wings. All images show adult wings oriented with distal to the right. (A) Control, engrailed (en)-Gal4, displaying single distally oriented trichomes. (B and C) en-Gal4 UAS-gish^IR (B) and FRT82-gish^e01759 clones (C) project multiple distally oriented trichomes. (D and E) Wild-type and gish LOF nota (dorsal thorax). Images show nota oriented with anterior to the top. (D) Control, pannier (pnr)-Gal4 notum, exhibits single posterior-oriented trichomes. (E) Many cells in pnr-Gal4 UAS-gish^IR tissue project multiple trichomes. (F–H) Wild-type and gish mutant adult eye sections. (F) Homozygous sevenless (sev)-Gal4 (sev-Gal4 2×) eyes display wild-type ommatidial orientation. (G and H) Homozygous sev>gish^IR (sev>gish^IR 2×; G) and gish^e01759 clones (H) exhibit misrotated ommatidia. Anterior is to the left. Diagrams on the bottom depict rhabdomere orientation; circles represent irregular photoreceptor number. Bars: (A–C) 25 µm; (D and E) 50 µm; (F–H) 10 µm.