Figure 5.
Figure 5. Model for how S1P triggers extrusion. S1P is produced in the dying cell and exported to neighboring cells. S1P binds to S1P2 and triggers formation and contraction of an actin-and-myosin II extruding ring to squeeze the dying cell out.

Model for how S1P triggers extrusion. S1P is produced in the dying cell and exported to neighboring cells. S1P binds to S1P2 and triggers formation and contraction of an actin-and-myosin II extruding ring to squeeze the dying cell out.

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