Figure 5.

Effects of EGFR on the behavior of border cell clusters. (A) Net movement of border cell clusters. Genotypes: slboGal4, UAS-10×GFP/+ (control) and indicated UAS transgenes. SEM is indicated; differences are significant at P < 0.001, except for control versus early DN-EGFR. (B) Tumbling index. (A and B) n = 6–14. (C) Extensions per frame (n > 170 per genotype and stage); differences between genotypes are significant (P < 0.001), except for control versus early DN-EGFR. (bottom) Average (Avr) size of front extensions and percentage of total extensions (in snapshots) that are front. (D and E) Position of border cells in stage 10 egg chambers. Genotypes: slboGal4, slbo1310-lacZ/+ and the indicated transgenes; EPgPvf1 drives Pvf1 expression (n = 100–900). The control showed a 99% complete migration (migr.).

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