Figure 6.
Figure 6. Syndecan-3 is required for the migration of immature interneurons in the developing telencephalon. (A–F) Coronal sections through the developing telencephalon of wild-type (syndecan-3+/+, A–C) and syndecan-3−/− embryos (D–F) showing calbindin and Tuj1 immunostaining. (C and F) Merged images of calbindin and Tuj1 stainings. (G) The graph depicts the mean number of calbindin-positive cells in the medial (mcp) and lateral (lcp) cortical plate (cp) and in the intermediate zone (iz) of the GE. (H) The intensity of Tuj1 staining is not altered in syndecan-3–deficient brains. (G and H) Error bars show SEM of three embryos (syndecan-3+/+, n = 3; and syndecan-3−/−, n = 3). *, P < 0.01. Bar, 80 µm.

Syndecan-3 is required for the migration of immature interneurons in the developing telencephalon. (A–F) Coronal sections through the developing telencephalon of wild-type (syndecan-3+/+, A–C) and syndecan-3−/− embryos (D–F) showing calbindin and Tuj1 immunostaining. (C and F) Merged images of calbindin and Tuj1 stainings. (G) The graph depicts the mean number of calbindin-positive cells in the medial (mcp) and lateral (lcp) cortical plate (cp) and in the intermediate zone (iz) of the GE. (H) The intensity of Tuj1 staining is not altered in syndecan-3–deficient brains. (G and H) Error bars show SEM of three embryos (syndecan-3+/+, n = 3; and syndecan-3−/−, n = 3). *, P < 0.01. Bar, 80 µm.

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