Synthetic lethal screens identify additional genes important for spindle disassembly. (A) Fraction of the genes found in the CDH1, KIP3, and SHE1 synthetic interaction profiles that have previously described roles in mitosis or meiosis. SL, synthetic lethal. (B) Frequency in which spindles disassembled after initiation of cytokinetic ring contraction in the indicated strains (n = 3 experiments each analyzing 20 disassembly events for each strain; mean ± SD). Analysis was performed similar to the experiments described in Fig. 2 A. Analysis of ipl1-321 mutants was performed at 37°C and compared with wild-type (WT) cells cultured at the same temperature.