Figure 3.
pVHL enhances MT growth recovery under nocodazole challenge. (A) Relative loss of EB3-GFP signal after the addition of 40 nM nocodazole to RCC-4 cells reconstituted with the empty retroviral expression vector pCMV(R) (VHL−/−) or with pCMV(R) expressing wild-type pVHL (VHL30). (B) Relative slowdown of growth and shrinkage speeds. (C) Relative slowdown of growth segment speeds. (D) Relative slowdown of gap/pause speeds. (E) Change in the frequency of gaps. (F) Relative change in the duration of segments.