Overexpression of GFP-BazS980A causes cuticle phenotypes similar to crb and sdt loss of function mutations. (a) Overexpression of GFP-Baz does not affect embryonic development and allows the formation of a normal cuticle. (b) Overexpression of the membrane-bound intracellular domain of Crb (Crb_intra) causes the formation of an ectopic cuticle. (c and d) Co-overexpression of Crb_intra and GFP-BazS980A (c) causes the same phenotype as overexpression of GFP-BazS980A alone (d). (e and f) Cuticle defects upon GFP-BazS980A overexpression are strongly suppressed when the embryo is at the same time mutant for lgl (e) or scrib (f). Genotypes are given in each panel. Bar, 100 µm.