Model summarizing the different effects of merotelic attachment on mitotic progression. Schematic representation illustrating the impact of merotelic attachment in control cells (left) and in cells with a defective spindle structure (right). In the control cells, the correction of merotelic attachment is coordinated with the onset of cytokinesis to avoid the formation of cut/anucleate. In cells with a defective spindle structure (ase1 mutant), this coordination is lost, leading to the appearance of a cut/anucleate phenotype and cell death. The different categories of cells were scored by live cell imaging using either a rad21-K1 ndc80-gfp cdc11-cfp myo2-gfp strain or an ase1Δ rad21-K1 ndc80-gfp cdc11-cfp myo2-gfp during mitosis from metaphase to cytokinesis and cell abscission. For clarity, the model does not include the percentage of cells showing merotelic Kt disruption (15% for control and 6% for ase1Δ).