Genetic analysis suggests that unc-108 (Rab2) mutations disrupt the trafficking or function of DCVs during the locomotion behavior. (A) unc-108 (Rab2) and egl-3 (PC2) mutations disrupt different functions of UNC-31 (CAPS) in the locomotion behavior. The graph compares the locomotion rates of wild type with the indicated mutants. All alleles are null deletion mutants. Mann-Whitney p-values between the indicated strains are also shown. Error bars are SEMs of 10 animals each. (B) unc-108; egl-3 double null mutants phenotypically resemble unc-31 null mutants. Representative adult animals are shown for each genotype. The body length of wild type is ∼1 mm, and all images have identical magnification. See also Videos 1–5.