unc-108 (Rab2) mutants have normal levels of neurotransmitter release from small synaptic vesicles. (A) Representative traces of electrically evoked excitatory postsynaptic currents recorded from the body wall muscles of wild type and the indicated unc-108 mutants. (B) Representative traces of endogenous miniature postsynaptic currents (minis) recorded from the body wall muscles of wild type and unc-108(ce365). (C) Mean amplitude of electrically evoked postsynaptic currents in wild type (WT; n = 21), unc-108(ce365) (n = 13), and unc-108(nu415) (n = 7). Mann-Whitney p-values of ce365 and nu415 versus N2 are 0.096 and 0.6, respectively. (D and E) Mean frequencies and amplitudes of minis recorded from the body wall muscles of wild type (n = 21), unc-108(ce365) (n = 13), and unc-108(nu415) (n = 7). Mann-Whitney p-values of each mutant versus N2 are all ≥0.4. (C–E) Error bars are SEMs.