Figure 7.
CED-9(R211E, N212G) is less effective in the promotion of mitochondrial fusion. (A) Schematic of the mitochondrial morphologies observed in embryos. (B) Transgenic lines overexpressing mitogfp in combination with ced-9(N158A, A159G, Q160A) (PHSmitogfp + PHSced-9(N158A, A159G, Q160A)) or ced-9(R211E, N212G) (PHSmitogfp + PHSced-9(R211E, N212G)) were analyzed by Nomarski optics and fluorescent microscopy. The outline of cells is indicated in the schematic of the mitochondrial network. Quantification of the different mitochondrial morphologies observed and the number of embryos and transgenic lines analyzed are indicated.
