Phenotypic signatures defined by clustering of the siRNA effects, and the biological features enriched in each cluster. Graphic representation of the mean scores of recorded features, showing the “phenotypic signature” of each cluster. The number of siRNAs in each cluster is indicated below the cluster name. Clusters with similar effects but with varying intensities are framed together. Tables on the right indicate biological features that are enriched in each cluster, with P values < 0.01. NE, no effect. Error bars represent standard deviation. (a) Clusters of FA morphology features. (b) Clusters of FA distribution features. (c) Clusters of cell shape features.