Figure 1.

cno mutants have defects in morphogenesis. (A) Domain structures and cno mutant. (B and C) Stage 7 wild-type (WT) or cnoR2 MZ embryos stained for Cno and antiphosphotyrosine (PTyr; insets) to show cell borders imaged on same slide. (D–J) Cuticles, anterior up. Genotypes are indicated. (E and F) cnoR2 zygotic mutants are shown. Arrows, head involution defects; arrowhead, dorsal closure defects. (G) cnoR2 MZ is shown. Only dorsal cuticle remains. (H) armXP33 MZ mutant (in eggshell) is shown, cuticle fragmented. (I) shgR69 zygotic mutant retains only dorsal cuticle. (J) Rap1 MZ mutant retains only dorsal cuticle (see Results for Rap1 data). FHA, forkhead-associated domain; DIL, dilute domain. Bars: (B and C) 10 µm; (D–J) 100 µm.

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