Figure 2.

MKLP1 properties (and the presence/absence of stable MTs) determine the amplitude of MKLP1 concentration in the furrow zone. Each of the eight panels, comprising frames from Video 2 , shows radial density plots of MKLP1s (in the same style, at the same time points, as in Fig. 1 F) taken from eight different simulations in 80-μm-diameter cells using different motor and/or MT properties summarized at the bottom of each panel. In all simulations except the one shown in G, stable MTs were present. In all simulations except the one shown in H, MKLP1s stall at MT tips. The main text explains the point each simulation makes and explains how the gray, white, and red radial density plots show the concentrations of MKLP1s near the cortex (gray and white) and in soluble form throughout the cell (red). See the online supplemental videos for the full simulations this figure summarizes.

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