Figure 2.
Geometries of kinetochore attachment in MUG. (A) Cells undergoing MUG were fixed and stained for chromatin, microtubules, and kinetochores. Images are maximum intensity projections of deconvolved z slices. Insets (single z slices) illustrate the types of microtubule–kinetochore attachments achievable in MUG: (1) merotelic, (2) monotelic, and (3) lateral. (B) Comparison of kinetochore attachments to spindle poles in normal mitosis versus MUG. Amphitelic or syntelic arrangements are not applicable (N.A.) for unpaired kinetochores.