KLP10A binds to both spindle poles and cortical microtubules. (A) Meiosis I spindles in fixed klp10A-gfp oocytes show pole bodies attached to cortical microtubules (arrows). (B) Fixed gfp–α-tubulin or klp10A-gfp oocytes treated with microtubule-destabilizing/stabilizing drugs show changes in GFP–α-tubulin (top) or KLP10A-GFP cortical microtubule signals (middle) and spindle length (bottom). Taxol causes increased KLP10A-GFP spindle fluorescence (arrows). Bars, 5 μm (A, two images at right, 3 μm).