The timing of syncytial mitoses is not affected in akt embryos. Chromosome dynamics in wild-type and akt1^q/akt1⁰⁴²²⁶ embryos expressing GFP-histone. (A) Histogram representing the percentage of nuclei that move into the interior of the embryo (nuclear fallout) during cycles 11, 12, and 13. Data were obtained from 20 wild-type and 20 akt1^q/akt1⁰⁴²²⁶ embryos. (B) Graphical representation of an idealized graph applied to chromosomes throughout mitosis (Yau and Wakefield, 2007). Parameters of interest are automatically obtained using this software, such as (i) rate of chromosome condensation, (ii) length of metaphase, and (iii) rate of chromosome segregation. (C) Chromosome dynamics during cycle 12 in wild-type (black) and akt1^q/akt1⁰⁴²²⁶ (red) embryos. Each line is the mean of 10 nuclei from a single embryo. Data were obtained from seven different wild-type or akt1^q/akt1⁰⁴²²⁶ embryos. Similar results were found for embryos in cycles 11 and 13 (unpublished data). See Videos 2 and 3 .